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16 June, 19:07

7) Which of the following is true about p53?

A) p53 is a tumor suppressor, that, when active, stops tumors from growing.

B) P53 is a protein.

C) When both copies of the p53 gene are mutated, cancer can result.

D) All of the above

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  1. 16 June, 19:11
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    D. All of the above

    Explanation:

    P53 is a tumor protein. It is often referred to as the "guardian of the genome". It can stop the cell from growing, repairs DNA and controls cell death, which is called apoptosis. As the cell is cycle goes on, p53 stops the growth of the cell when there is an error or damage in the DNA. This action prevents the defective cell from replicating. The p53 then signals the production of proteins that repair DNA. If the DNA is not fixable, it programs apoptisis.

    If by some chance that the p53 gene are mutated, then it cannot do those functions, which may result in cancer or the uncontrolled replication of defective cells.
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