You are studying a sub-strain ofpathogenic E. coliO157, which has a5.5Mb (5,500,000 nucleotide bases) genome, a pseudogene that is 2 Kb (2,000 nucleotidebases) long, and an elevated mutation rate because it has a defectiveDNA proof-reading gene mutS (μg=0.1per genome replication). You start a culture from a single cell. At what population size do we expect to see the first mutation arise in the pseudogene?
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