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6 November, 23:04

For two autosomal dominant genes, what is the probability that a cross between two heterozygotes (i. e. AaBb x AaBb) will produce an offspring with the recessive trait for both genes?

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  1. 6 November, 23:14
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    1 in 16

    Explanation:

    When two heterozygotes (AaBb x AaBb) for two autosomal genes are crossed the expected probability for the offspring is 9 A-B-, 3 A-bb, 3 aaB - and 1 aabb. In other words, out of sixteen offspring, 9 are expected to be dominant on both genes (either homozygous AA or BB or heterozygous Aa or Bb), 3 are expected to be dominant on the A gene but recessive on the b gene, 3 are expected to be recessive on the a gene but dominant on the A gene, and only 1 is expected to be recessive on both genes aabb.
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