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20 April, 08:03

Transcriptional regulation involve interactions between proteins and regulatory sequences (DNA). The two types of regulation are Negative Control and Positive Control. What types of statements regarding these two types of control is correct?

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  1. 20 April, 08:17
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    Regulation

    Explanation:

    Operons are the structural unit of gene organisation

    If product of regulatory gene binds to the upstream of promoter and induce expression of operon genes, system is called positively controlled whereas if product of regulatory gene binds to the operator and prevents expression of operon genes, system is called negatively controlled

    An inducer binds to the repressor and induce conformational changes causing dissociation of repressor from operator therefore in absence of repressor RNA Polymerase binds to the promoter and starts transcription of genes

    In some cases, A co-repressor binds to the repressor and activate it as a result activated repressor binds to the operator and prevent binding of RNA Polymerase thus blocks transcription of structural genes
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