In the sickle-cell anemia mutation, the 5'-GAG-3' codon for glutamic acid becomes the 5'-GUG-3' codon for valine. Assuming a single nucleotide substitution accounts for this mutation, what is the change in the DNA?

Question

Marble

Chemistry

20 October, 06:54

In the sickle-cell anemia mutation, the 5'-GAG-3' codon for glutamic acid becomes the 5'-GUG-3' codon for valine. Assuming a single nucleotide substitution accounts for this mutation, what is the change in the DNA?

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Answers (1)

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Ramiro Marquez · Answer 1

The adenine is substituted by the uracil

Explanation:

In this mutation, the adenine nucleotide of the glutamic acid was replaced wrongly for an uracil (this is actually a nucleotide characteristic of the RNA and not the DNA). This process is called a mutation by substitution.