Which of the following areas is the most inaccessible to humans?

Papua New Guinea

Micronesia

Guam

South Pole

Among the regions given in the question, South Pole is the most inaccessible to humans. The correct option among all the options that are given in the question is the last option. The weather in the South Pole is so harsh that it is almost killer conditions for normal humans and so most of the places are almost inaccessible.