An effect of diseases that were part of the columbian exchange was that

As Europeans crossed the Atlantic, they carried with them flowers, pets, and viruses that transformed experiences and sceneries on both sides of the sea. These two-way transactions within the Americas and Africa are identified collectively as the Columbian Exchange.

Of all the products in the Atlantic World, sugar determined to be the most powerful. Moreover, with the exchange of products, there was also the threat of the major killing virus which was the part of exchange incorporate smallpox, measles, raging cough, chicken pox, bubonic plague, typhus, and malaria which proves very deadly and killed the inhabitants of the native places.

Killed a great number of indians that had not yet been exposed to the diseases