What did the germanic tribes of Eastern Europe finally manage to do in the ad 200s?

The first time was called The Sack of Rome which occurred on 24 August 410. The city was attacked by the Visigoths led by King Alaric. At that time, Rome was no longer the capital of the Western Roman Empire, having been replaced in that position first by Mediolanum in 286 and then by Ravenna in 402. Nevertheless, the city of Rome retained a paramount position as "the eternal city" and a spiritual center of the Empire. The second time was when the Vandals under Gaiseric captured and plundered Rome in June 455.