When will you need hexadecimals in life?

The following would be advantages:

The numbers would have less digits overall. 100 in hexadecimal is two hundred and fifty six, compared to one hundred in decimal.

Dividing by sixteen (and by powers of sixteen) is easier in hexadecimal than it is in decimal.

Knowing at a glance if a number is divisible by four, by eight, or by sixteen is easier in hexadecimal than it is in decimal.

But there would also be disadvantages. The first disadvantage would probably be requiring to learn the multiplication tables for all numbers up to fifteen, instead of for all numbers up to nine.

Hexadecimal numerals are widely used by computer system designers and programmers, as they provide a human-friendly representation of binary-coded values. Each hexadecimal digit represents four binary digits, also known as a nibble, which is half a byte.