Endothelial cells give rise to macrophages after entering extravascular tissues true or false

The answer is false.

Macrophage is one of the immune cells that comes from reticuloendhotelial system while the endothelial cells refer to the cell that lining inner part of the blood vessel. Endothelial cell is a single layer squamous cell that has main role in protecting the vessel physically. Macrophage has a role in immunity function.