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6 January, 19:01

Which of the following would not be a potential side effect of standard antimicrobial drugs?

Group of answer choices

inhibition of host protein synthesis

disruption of the host's normal microbiota

damage to the host's kidneys

allergic reactions in the host

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  1. 6 January, 19:10
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    Inhibition of host protein synthesis would not be a potential side effect of standard antimicrobial drugs.

    Explanation:

    Antimicrobial drugs that are specific to inhibit the protein synthesis only target the units of 70S ribosomes. Hence, the ribosomes of eukaryotes remain unaffected. The microbiota present in digestive system is prokaryotic and gets affected by the antibiotics.

    Antibiotics can damage the renal tubular cell of the kidney on long term use. As the excretion of toxic drug bi-products and other metabolites takes place from the kidney hence it is highly exposed to these end products.

    For example, aminoglycosides have been shown to be nephrotoxic (damaging to kidney), Allergy reactions such as hypersensitivity reactions and anaphylactic reactions such as asthma, coughing, hives are the other side effects of antimicrobial drugs because the cells of immune system recognize these drugs as foreign molecules and attacks them which causes the allergy reactions.
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