Which situation would inhibit a Krebs cycle from functioning in an organism's cells?

If the formation of Acetyl CoA does not occur.

Explanation:

A Krebs cycle which is also known as the citric acid cycle, is a cycle showing parts or series of chemical reactions to generate energy by aerobic organisms.

The acetyl coA is converted to two carbon molecule, that is, oxaloacetate, which enters the Krebs cycle.