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8 February, 07:38

In the salvage of purines, hypoxanthine-guanine phosphoribosyl transferase (HGPRT) is responsible for which of the following processes:

a) guanine to guanosine monophosphate (GMP) b) inosine monophosphate to inosinec) adenine to adenosine monophosphate (AMP) d) hypoxanthine to xanthine

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  1. 8 February, 08:02
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    a) guanine to guanosine monophosphate (GMP)

    Explanation:

    Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) is a transferase enzyme which is responsible for the conversion of guanine to guanosine monophosphate (GMP) and of hypoxanthine to inosine monophosphate. The primary function of HGPRT to salvage the purines from the DNA that has been degraded and thus reintroduce the purines into the purine synthetic pathway.
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