A nerve cell with normal levels of intracellular calcium is treated with intracellular IP3, which opens calcium channels in the endoplasmic reticulum. What would the transmembrane voltage across the plasma membrane of the cell (that is, the voltage of the cytoplasm relative to the extracellular solution bathing the cell) if this occurs and calcium has no other effects on the cell

Question

Salvador Hoffman

Biology

30 January, 16:25

A nerve cell with normal levels of intracellular calcium is treated with intracellular IP3, which opens calcium channels in the endoplasmic reticulum. What would the transmembrane voltage across the plasma membrane of the cell (that is, the voltage of the cytoplasm relative to the extracellular solution bathing the cell) if this occurs and calcium has no other effects on the cell

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Jorge Baird · Answer 1

M. P = 140.46 Vm

Explanation:

Membrane potential can calculated using the following equation:

(61/z) ln ([X]out/[X]in)

where z is the charge of Ca2 + ion and X represent the concentrations By applying necessary calculations ...

Membrane potential = (61 / 2) ln (100 x 10^-3 / 1 x 10^-3)

= 30.5 x 4.60 = 140.46 Vm