The process by which a cell in culture acquires the ability to divide indefinitely, similar to the division of cancer veils; a change in genotype and phenotype due to the assimilation of external DNA by a cell, when the external DNA is from a member of a different species, transformation results in horizontal gene transfer. The exchange contains homologous DNA segments. The cell is now a recombinant, its chromosome contains DNA derived from 2 different cells
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