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19 August, 11:52

Identify the enzyme which catalyses both oxidation as well as phosphorylation events during the same reaction in glycolysis?

a. Pyruvate Kinase

b. Phosphoghycerate kinase

c. Phosphofructokinase 1

d. Glyceraldehyde 3 phosphate dehydrogenase

e. Triose phosphate isomerase

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  1. 19 August, 12:13
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    D. Glyceraldehyde 3 phosphate dehydrogenase

    Explanation:

    The enzyme glyceraldehyde 3 phosphate dehydrogenase catalyzes the oxidation of glyceraldehyde 3-phosphate into 1,3-bisphosphoglycerate. This is the first reaction of the payoff phase of glycolysis.

    The inorganic phosphate serves as a donor of the phosphate group while NAD + serves as an oxidizing agent. During the reaction, the aldehyde group of glyceraldehyde 3-phosphate is oxidized into a carboxylic acid anhydride with phosphoric acid.
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