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24 August, 02:01

Phenylketonuria (PKU) is an autosomal recessive genetic disorder. The frequency of homozygotes with this disorder is 0.0001. What percentage of the population is heterozygous?

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  1. 24 August, 02:19
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    Answer: The percentage of heterozygous population is 99%

    Explanation:

    According to the Hardy-Weinberg Equilibrium equation, the homozygous recessive individuals are represented by the q^2 term

    Thus, q^2 = 0.0001

    q = √0.0001 = 0.01 or 1%

    Now, to calculate the percentage of heterozygous individuals in the population: subtract percentage of homozygotes from 100%

    i. e 100% - 1% = 99%

    Therefore, the percentage of heterozygous population is 99%. Also, this means 1 out of 100 people in the population suffer from Phenylketonuria (PKU).
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