An imbalance from the homeostasis perspective is considered to be

When there is an imbalance from the homeostasis of the body, a disorder or disease may result. Homeostasis establishes balance and equilibrium of the internal and external part of the body. If this balance or ideal levels are interrupted, the body may correct it by making all system work together or the problem may worsen based on certain influences and may not allow normal functioning of the organism, by either deficiency or toxicity.

Moreover, some factors that influence the body’s ability to maintain homeostatic balance are genetics, lifestyle choices and environmental exposure.