Describe how the structure of a prokaryotic chromosome differs from the structure of a eukaryotic chromosome.

The structure of prokaryotic chromosome differs from the structure of eukaryotic chromosome by following ways:

A prokaryotic chromosome is shorter than the eukaryotic chromosome. In prokaryotes, the circular chromosome is held in the cytoplasm in a region called nucleoid whereas in eukaryotes chromosomes are stored within a structure called the nucleus. Prokaryotic chromosome comprises only a single origin of replication whereas the eukaryotic chromosome carries multiple origins of replication. Prokaryotic chromosome consists of covalently closed (loop) circular DNA whereas the eukaryotic chromosome consists of linear DNA not circular.