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31 August, 14:51

Suppose that each β-adrenergic receptor bound to epinephrine converts 100 molecules of the G? subunit to the GTP-bound form, G? s. If each molecule of activated adenylate cyclase produces 1000 molecules of cAMP per second, how many molecules of cAMP are produced in 10 seconds after the formation of a single complex between epinephrine and the β-adrenergic receptor? Assume the pathway is fully responsive.

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  1. 31 August, 14:52
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    The correct answer is 10^5*10 molecules of cAMP are produced.

    Explanation:

    It is given that when each molecule of epinephrine combines with the adrenergic receptor the transformation of 100 molecules of G-alpha takes place into their stimulated GTP form, which further stimulates adenylate cyclase. This stimulated adenylate cyclase further give rise to 1000 molecules of cAMP per second.

    Therefore, in one second the production of 100 * 1000 or 10^5 cAMP molecules is taking place.

    Thus, in 10 seconds, the production of 10 * 10^5 cAMP molecules will take place.
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