Sign In
Ask Question
Raymond Ward
Biology
25 August, 17:37
What is CAP? How does CAP work?
+3
Answers (
1
)
Kadin Dougherty
25 August, 18:03
0
The Escherichia coli catabolite gene activator protein (CAP) is a DNA binding protein involved with the transcription of several genes, including those that code for enzymes involved in the metabolism of certain sugars (i. e. lactose, maltose, and arabinose.) Basically, CAP is responsible for the global regulation of carbon utilization. Upon binding cAMP, CAP binds to a conserved DNA sequence from which it can either activate or repress transcription initiation from various promoters. In some cases clusters of several promoters are all controlled by a single cAMP-CAP complex bound to the DNA.
Once CAP has bound cAMP, the protein exhibits a higher affinity for a specific conserved DNA sequence. When the intracellular level of cAMP increases, the second messenger is bound by CAP and the cAMP-CAP complex binds to the DNA. Once bound, it is able to stimulate the transcription of the aforementioned genes. DNA bound by the CAP-cAMP complex is bent by ~90 degrees. This DNA bend, coupled with a protein-protein interaction between CAP and RNA polymerase is thought to be the mechanism by which CAP regluates transcription initiation on the chromosome.
Comment
Complaint
Link
Know the Answer?
Answer
Not Sure About the Answer?
Find an answer to your question 👍
“What is CAP? How does CAP work? ...”
in 📗 Biology if the answers seem to be not correct or there’s no answer. Try a smart search to find answers to similar questions.
Search for Other Answers
You Might be Interested in
Question: a. The teacher puts a sugar cube into a container of warm water. Eventually the sugar cube is no longer visible. What type of change is this and why?
Answers (2)
Which of these is not an example of intracellular communication? A. Charged ions distributed across a plasma membrane B. Water regulation by a cell's central vacuole C. A signal is translated to cause a muscle to contract D.
Answers (1)
How many kingdoms are in the domain Eukarya? one four six nine
Answers (2)
Which diagram correctly displays the order of events during egg formation?
Answers (1)
An individual has a nutrient deficiency due to a poor diet and is missing a specific amino acid, how would this affect the ability of the cell to synthesize particular proteins?
Answers (1)
New Questions in Biology
Which of the hormones below is responsible for facultative water reabsorption? Question options: aldosterone ADH atrial natriuretic peptide thyroxine
Answers (2)
An unknown species is discovered to have diploid cells that contain 130 chromosomes. How many chromosomes would be found in the gametes of this species were it to reproduce?
Answers (1)
What do most experiments test? 1:Scientific theories 2:Falsifiability of hypotheses 3:Accuracy of information 4:Predictions based on hypotheses
Answers (1)
How do substances change after chemical reaction? A. they change phase B. their atoms are rearranged C. their atoms lose electrons D. they lose mass
Answers (1)
What types of cells are produced in process for females? for males?
Answers (1)
Home
»
Biology
» What is CAP? How does CAP work?
Sign In
Sign Up
Forgot Password?