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19 October, 11:53

Carriers of the sickle-cell allele (i. e. those with a heterozygous genotype) are fittest in environments with high frequencies of:

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  1. 19 October, 13:47
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    Individuals who are heterozygous for the sickle-cell allele suffer less from the attack of malaria because a small percentage of the red blood cells are sickle-shaped. They are more resistant to malaria than individuals who have two copies of the normal haemoglobin allele. Heterozygous individuals have a better chance of surviving and reproducing in regions where malaria is prevalent since they do not fully contract the disease.
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