The practitioner carefully monitors his client who exhibits hemoglobin S (HbS) genes. The practitioner know that the client is predisposed to life-threatening infection due to damage by HbS to which of the following organs?

-Spleen

-Lungs

-Heart

-Pancreas

Answer is spleen.

Explanation:

Spleen is an organ in the body, and responsible for various actions like blood purification, removal of damaged blood cells and production of white blood cell.

Splenic sequestation is a situation where the spleen becomes enlarged. And this is common to sickle cell anemia people, especially the children. That is, the shape of the red blood cells are sickle.

In this case, the spleen becomes bigger, and the amount of oxygenated blood cells in the body are reduced.