What is now considered to be a preferred nucleus appearance discriminator between myelocytes and metamyelocytes instead of the degree of indentation of the nucleus?

Nuclear chromatin clumping is increased in the metamyelocytes, nuclei disappears and granules are mostly secondary

Explanation:

Metamyelocyte is the cell that is undergoing granulopoiesis and is derivative of a myelocyte. It is characterized by the bent nucleus type of appearance, cytoplasm consists of the cytoplasmic granules and visible type of nucleoli are absent. Myelocytes are the cells occurring in a bone marrow; cells with cytoplasmic granules which that produces granulocytes of the blood. It doesnot occur normally in the blood as in leukaemia.