Gram-negative bacterium Vibrio cholera produces a protein (cholera toxin) that is responsible for cholera symptoms: extensive loss of water and Na through continuous diarrhea, which can be fatal. The toxin tightly binds specific sites on the plasma membrane of intestinal cells, where it prolongs the activation of adenylate cyclase (AC).
A. What effect does the cholera toxin have on cAMP levels in intestinal cells?
B. Based on the provided information: suggest a role for cAMP in intestinal cells under normal conditions.
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