How does the response to acetylcholine in the presence of nifedipine compare to the response to acetylcholine without nifedipine? what response is there to nifedipine by itself (if any) ?

Nicotinic acetylcholine receptors (nAChR), are ligand-gated ion channels and they can be a Na+, K + and Ca2 + ion channel. Since nifedipine is a Ca2 + channel blocker (Ca2 + channel antagonist), it might inhibit the response of acetylcholine (if its receptor is Ca channel).