Kornberg, in his experiments to demonstrate the function of DNA polymerase I, sought to show that DNA Pol 1 was capable of replicating biologically active DNA. What is the definition of biologically active DNA in this context?

Kornberg performed the experiment to identify the molecules which could be able to replicate the DNA. He used a bacterial strain and bacteriophage which could infect the bacteria by incorporating its DNA.

He was able to detect an enzyme which cold assemble all the molecules to form a new DNA strand and named the enzyme as DNA polymerase.

This DNA polymerase can replicate biologically active DNA in which biologically active means that a biological active progeny DNA of phage was which is very accurate and is viable is produced by the bacteria using the enzyme DNA polymerase.