17 February, 03:30
If the a and b loci are 20 m. u. apart in humans and an AB/ab woman mates with an ab/ab man, what is the probability that their first child will be Ab/ab
17 February, 05:11
The distance between the given two loci is 20 mu. This means that the recombination frequency between these two loci is 20% and the heterozygote will form 20% recombinant gametes and rest 80% parental type gametes. Therefore, the heterozygous woman AB/ab will form a total of 20% recombinant gametes. The proportion of each recombinant gamete will be 20/2 = 10%.
Gametes formed by the woman = 10% Ab, 10% aB, 40% AB, and 40% ab
Gametes formed by the man = All ab (since the man is homozygous for both loci).
Therefore, proportion of Ab/ab genotype = 10% Ab (female gamete) x ab (male gamete) = 10% Ab/ab
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» If the a and b loci are 20 m. u. apart in humans and an AB/ab woman mates with an ab/ab man, what is the probability that their first child will be Ab/ab