Sickle cell anemia is an autosomal recessive disorder. a person with the disorder and a person that is a carrier mate. (a carrier has the allele for the trait but does not express it.) what is the chance that their offspring will develop sickle cell anemia?

Question

Meghan Maddox

Biology

30 January, 10:17

Sickle cell anemia is an autosomal recessive disorder. a person with the disorder and a person that is a carrier mate. (a carrier has the allele for the trait but does not express it.) what is the chance that their offspring will develop sickle cell anemia?

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Skylar Blanchard · Answer 1

Let's tag the person with a disorder as "aa" as he has both recessive alleles. The carrier is "Aa" which means he has one dominant allele and one recessive allele. Crossing Aa x aa will yield 2Aa and 2aa which means there is a 50% chance that their offspring will have sickle cell anemia and 50% chance that their offspring will become a carrier.