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30 May, 15:40

A series of enzymes catalyze the reaction X Y Z A. Product A binds to the enzyme that converts X to Y at a position remote from its active site. This binding decreases the activity of the enzyme. With respect to the enzyme that converts X to Y, substance A functions asa. a coenzyme. b. an allosteric inhibitor. c. the substrate. d. an intermediate. e. a competitive inhibitor.

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  1. 30 May, 16:06
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    Option B, an allosteric inhibitor.

    Explanation:

    As the enzyme activity decreases, it is not possible for A to be a coenzyme (most likely would increase the enzyme activity), a substrate (increases activity of enzyme by Le Chatler's principle) or an intermediate (no effect). A is unlikely to be a competitive inhibitor as this would not decrease the activity of the enzyme, only reduce the rate of conversion of substrate to product. A is most likely an allosteric inhibitor which binds to another site on the enzyme (other than the active site), resulting in a change in conformation of the enzyme which reduces the enzymatic activity.
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