How are transfusion reactions type II responses? What happens in a transfusion reaction?

Explained

Explanation:

Type II response can be defined as an antibody-dependent process in which specific antibodies bind to antigens and results in tissue damage. Transfusion reaction is a type II response because here the mismatched RBC's are rapidly destroyed by specific preformed antibodies (anti-ABO or - Rh) and complement.

Transfusion reactions takes place when incompatible blood products are transfused into a patient's circulation. This triggers the patient's immune system and consequently donor RBC's are destroyed by antibodies in the recipient's circulation. This is usually seen when antigen-positive donor RBC's are transfused into a patient who has preformed antibodies to that antigen.