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28 March, 13:18

In a sample of 2,400 people, 1,482 were found to have the dominant (taster) phenotype. Assuming that the population is in Hardy-Weinberg equilibrium, approximately how many individuals in the sample are expected to be heterozygous for TAS2R38?

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  1. 28 March, 13:42
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    1128.

    Explanation:

    The dominant taster phenotype is 1482.

    The recessive taster phenotype = 2400 - 1482 = 918.

    Recessive phenotypes = 2400 - 1482 = 918

    The recessive phenotype frequency = q² = 918 / 2400 = 0.38.

    the recessive allele frequency q = √0.38 = 0.62.

    The dominant allele frequency, p = 1-q = 1 - 0.62 = 0.38

    The heterozygous frequency = 2pq = 2 * 0.38 * 0.62 = 0.47.

    The heterozygous individual in the population = 0.47 * 2400 = 1128.

    Thus, the answer is 1128.
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