In which order do the necessary enzymes act to repair a thymine dimer by nucleotide excision repair? a) nuclease, dna polymerase, rna primaseb) helicase, dna polymerase, dna ligasec) dna ligase, nuclease, helicased) dna polymerase, rna polymerase, dna ligasee) nuclease, dna polymerase, dna liga?

Question

Karen Mcmillan

Biology

27 May, 06:33

In which order do the necessary enzymes act to repair a thymine dimer by nucleotide excision repair? a) nuclease, dna polymerase, rna primaseb) helicase, dna polymerase, dna ligasec) dna ligase, nuclease, helicased) dna polymerase, rna polymerase, dna ligasee) nuclease, dna polymerase, dna liga?

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Yaritza Gould · Answer 1

The order for the necessary enzymes that act to repair a thymine dimer by nucleotide excision repair is Endonuclease, DNA polymerase I, DNA ligase. Thymine dimer repair may be done by two mechanisms; Photoreactivation repair, the pre enzyme activated by blue light breaks the dimer restoring the normal base pairing. The other method is excision repair; where the uvr system excises the dimer, and the gap is filled in by the proof-reading activity of DNA polymerase I.