Inherited defects in nucleotide excision repair are a known cause of what disease?

a. xero pigmentosum (XP)

b. diabetes

c. AIDS

d. albinism

e. heart disease

The correct option is: a. xero pigmentosum (XP)

Explanation:

Nucleotide excision repair is a method to repair the damaged DNA. This method involves the removal of the DNA segment damaged by the harmful ultraviolet radiations. In this mechanism, the damaged single-stranded DNA segment is recognized and removed.

This method is used in the treatment of in-born genetic mutations of nucleotide excision repair proteins in humans.

Example: Xeroderma pigmentosum and Cockayne's syndrome