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7 July, 15:35

Classify the mutations as somatic or inherited

A. Mutations in the KRAS gene in lung cells promote continuous cell growth

B. Mutations of the BRAC1 gene in egg cells lead to breast cancer

C. Mutations in the FRG2 gene in sperm cells lead to loss of muscle mass.

D. Mutations of the BRAF gene in skin cells promote uncontrolled cell division.

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  1. 7 July, 15:51
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    Somatic mutations : option (A) and option (D).

    Inherited mutations : option (B) and option (C).

    Explanation:

    Mutations are permanent changes in the genetic material due to alterations in DNA sequence. Mutations may be somatic or inherited (or germline).

    Somatic mutations are those mutations that arise in somatic or normal body cells and cannot transfer from parents to their offspring. As skins cells and lung cells are somatic cells, option (A) and (D) represent somatic mutations.

    Inherited mutations are those mutations that arise in sex cells (gamete forming cell) and transfer from parents to their offspring due to transfer as these cells form mutated gametes. As egg cells and sperms cells are sex cells, option (B) and (C) represent inherited mutations.
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