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26 July, 23:01

Regulatory Molecule A (RM-A) can bind to Enzyme X and also Enzyme Y. Is it likely that RM-A can be a positive regulator for Enzyme X and a negative regulator for Enzyme Y? Is it likely that RM-A can be both a positive and a negative regulator for Enzyme X? Why or why not?

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  1. 26 July, 23:20
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    RM-A can be both a positive and a negative regulator for Enzyme X

    Explanation:

    It is imperative to obtain more comprehensive information on the signaling pathways in order to assess the regulatory role of the RM-A molecule on X and Y enzymes.

    Enzymes are modulated by molecules that are capable of increasing or reducing enzymatic activity, which are referred to as activators and inhibitors, respectively.

    Fructose 2,6-bisphosphate is an essential allosteric regulator that activates phosphofructokinase 1 (PFK1) and thus is capable of increasing the glycolysis rate in response to insulin. On the other hand, an inhibitor may be a pharmaceutical drug used to compete with a substrate for binding to the active site of the enzyme. For instance, the methotrexate chemotherapy drug is known to be a competitive inhibitor.
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