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12 June, 10:28

How might a single hormone have drastically different effects in

different cells? Propose several different mechanisms.

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  1. 12 June, 10:54
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    The correct answer is "There are several mechanisms that explain why a hormone have different effects in different cells. These mechanisms include: multiple receptors for the same hormone, a single receptor coupled to different pathways and hormones interacting with receptors for other molecules".

    Explanation:

    Hormones are among the most versatile molecules of the body, responsible for different biological processes such as human growth, sex development and metabolisms. Hormones are responsible of these complex biological processes because they have drastically different effects in different cells. There are several mechanisms that explain why a hormone have different effects in different cells. These mechanisms include:

    - Multiple receptors for the same hormone. For instance, there are multiple receptor for dopamine, a hormone and neurotransmitter responsible for different functions such as movement, memory, sleep and motivation.

    - A single receptor coupled to different pathways. Most hormone receptors act with a cascade of signaling. This in consequence results in a single receptor interacting with different molecules having multiple effects.

    - Hormones interacting with receptors for other molecules. One example is the action of one metabolite of progesterone named allopregnanolone. This metabolite interacts with GABA-A receptor, which gives it anxiolitic properties.
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