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20 October, 10:14

For mitochondria where an uncoupler for oxidative phosphorylation is present, which statement is TRUE?

a) The rate of NADH reoxidation will decrease relative to coupled mitochondria

b) The citric acid cycle will be inhibited relative to uncoupled mitochondria.

c) The P:O ratio for FADH2 wilt increase relabve to uncoupled mitochondria.

d) The amount of ATP generated from FADH2 will be fess than the amount of ATP generated from NADH.

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  1. 20 October, 10:39
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    The correct answer is statement d.

    Explanation:

    In oxidative phosphorylation that takes place in mitochondria, the uncouplers prevent the coupling in between the phosphorylation reactions and electron transport, and therefore, prevent the synthesis of ATP without influencing the ATP synthase and respiratory chain.

    The uncoupler always exhibits its influence on the synthesis of ATP. The 2,4-dinitrophenol functions as an uncoupler at the time of oxidative phosphorylation. The NADPH and FAD functions as an electron carrier.
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