A father with myotonic dystrophy has three daughters who are all carriers of the mutant allele and two sons who are unaffected noncarriers. the three daughters have six sons, of which four are affected and two are not, and four daughters, of which two are carriers and two are not. From this description, what type of mutation is probably responsible for myotonic dystrophy?

Question

Alfred Pruitt

Biology

7 June, 06:26

A father with myotonic dystrophy has three daughters who are all carriers of the mutant allele and two sons who are unaffected noncarriers. the three daughters have six sons, of which four are affected and two are not, and four daughters, of which two are carriers and two are not. From this description, what type of mutation is probably responsible for myotonic dystrophy?

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Answers (1)

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Roberto Watkins · Answer 1

Inherited Autosomal Dominant Mutations

Explanation:

The mutations in DMPK gene or ZNF9 gene contribute to the onset of Muscular Dystrophy. This is a type of inherited disorder that can run in families and due to it's autosomal transfer nature, it affects both sexes equally.