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11 November, 16:12

Suppose 36% of a remote mountain village cannot taste PTC and must, therefore, be homozygous recessive (aa) for the PTC non-taster allele. If this population conforms to Hardy-Weinberg expectations for this gene, what percentage of the population must be homozygous (AA) for the PTC taster allele?

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  1. 11 November, 16:16
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    16%

    Explanation:

    The frequency of homozygous recessive genotype in the given population = 36% or 0.36

    So, the frequency of the recessive non-taster allele in the given population would be = square root of 0.36 = 0.6

    Since the population is in HWE, the frequency of the dominant allele for this locus in the population = 1 - frequency of the recessive allele = 1-0.6 = 0.4

    Therefore, the frequency of the homozygous dominant genotype in the given population = 0.4 x 0.4 = 0.16 or 16%
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