How do chromosomes differ in prokaryotes and eukaryotes?

The major difference between prokaryotes and eukaryotes is the presence, in eukaryotes, of a cell nucleus. This nucleus contains the DNA, bound in chromosomes, of eukaryotic cells, where it is transcribed to mRNA which is cut and spliced before being passed to the ribosomes for protein synthesis. There are about 80 subunits in the ribosomes.