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23 May, 18:18

Acho ndroplasia is caused by an autosomal dominant allele and individuals who inherit two copies of the allele do not survive to birth. what is jennifer's genotype for the gene involved in acho ndroplasia? what is bill's genotype for the same gene? jennifer and bill hope to have a child. what is the likelihood that they will give birth to a child with acho ndroplasia? what is the likelihood that they will give birth to a child without the condition?

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  1. 23 May, 18:44
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    If both, Jenifer and Bill are the

    carriers (have one allele for the acho ndroplasia) that theirs genotypes are Aa (A is dominant, a is recessive allele). In this case:

    P: Aa x Aa

    F: AA Aa Aa aa

    This means that ¼ (25%) is the possibility for child to have acho ndroplasia.

    Second case is if one of the parents have homozygous recessive genotype aa (not having allele for acho ndroplasia):

    P1: Aa x aa

    F: Aa Aa aa aa

    This means that none of the child will inherit both alleles.
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