Which of the following is not an observation or inference on which natural selection is based? There is heritable variation among individuals. Species produce more offspring than the environment can support. Only a fraction of an individual's offspring may survive. Individuals whose characteristics are best suited to the environment generally leave more offspring than those whose characteristics are less well suited. Poorly adapted individuals never produce offspring.

The correct answer is - poorly adapted individuals never produce offspring.

Explanation:

The process in which an organism adapt according to their environment tends to survive and reproduce more than the one that do not adapt termed as natural selection.

Natural selection was first presented by Charles Darwin and it is considered as the main reason behind the evolution. So the poorly adapted individuals reproduce less.

Thus, the correct answer is option - poorly adapted individuals never produce offspring.

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