Which of the following resistance mechanisms is the most nonspecific to a particular class of antimicrobials?

drug modification

target mimicry

target modification

efflux pump

The efflux pump is the most nonspecific to a particular class of antimicrobials.

Explanation:

Antimicrobial -

An antimicrobial, the agent which destroys or kills the microorganism or inhibits their growth.

And these microbes can even develop resistance mechanism which involves the inhibiting the accumulation of the antimicrobial drug.

This is very common among the gram - negative pathogens and hence, involve changes in the outer lipid membrane composition, porin channel concentration and porin channel selectivity.

The gram - negative and gram - positive pathogens bacteria produces efflux pumps that can actively transport the drug out of the cell and thereby prevents the accumulation of the the drug.