Why would there be cause for concern if a young pregnant mother is rh-, her husband is rh, and this is their second child?

If the mother was given RhoGAM before or shortly after the birth of the first child, there

is little concern, because the RhoGAM prevented the mother from sensitizing herself

against her child. If she did not take RhoGAM, there is a chance the second child will

develop erythroblastosis fetalis and die before birth.

Because of a condition called eythroblastosis fetalis.

In this condition, the mother immune system attack the baby red blood cell destroying them. During her first child is when she is immunized against the red cell, the second child is when the attack going to happen