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23 April, 15:58

In a person with MCAD deficiency, if the body has excess glucose stores, which electron transfer intermediates are likely to accumulate? How does this change if the body is energy depleted?

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  1. 23 April, 16:24
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    In high glucose-NADH and FADH2

    In depletion case - NAD + and FAD+2.

    Explanation:

    MCAD (Medium-chain acyl-CoA dehydrogenase) deficiency may be defined as inherited disorder in which the body's ability to breakdown the fat decreases and converting them in energy.

    Excess glucose stores: The presence of excess glucose prevents the proton gradient to transfer electrons in the electron transport chain. This causes the buildup of NADH and FADH2.

    Low energy state: This state needs ATP that decrease the carriers and causes the buildup of NAD + and FAD+2.
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