In the human body, which of the following is considered an external defense in the prevention of disease? Mucous Histamines Antibodies Fever

Mucous is a sticky substance which traps bacteria and other pathogens.

Because mucous isn't released in the blood, it's an external defense.

Histamines are released in the bloodstream, making it an internal defense.

In the biology notebook I wrote right this:

Histamines ⇒ a compound that is released by cells in response to injury and in allergic and inflammatory reactions, causing contraction of smooth muscle and dilation of capillaries.

So, the answer is "Histamines".