Which cellular dysfunction is responsible for the manifestations of cystic fibrosis? abnormal chloride channel proteins allow increased sodium and water reabsorption. thickened peripheral proteins bind with phospholipids to block water absorption. extra integral proteins develop and block cellular fluid transport. transmembrane proteins transport additional water into cells?

Abnormal chloride channel proteins allow increased sodium and water reabsorption

Explanation:

Persons with cystic fibrosis have a defective CFTR gene. The causes the abnormal development of the cystic fibrosis transmembrane conductance regulator protein that is responsible for balancing water and salts across the membrane especially in epithelial cells that produce mucus and sweat and secretory enzymes. This causes the production of abnormally thick secretions that block the ducts.