Misinterpreting her physician's instructions, a 69-year-old woman with a history of peripheral artery disease has been taking two 325 mg tablets of aspirin daily. how has this most likely affected her hemostatic status? a. irreversible acetylation of platelet cyclooxygenase activity has occurred. b. she is at risk of developing secondary immune thrombocytopenic purpura (itp). c. the binding of an antibody to platelet factor iv produces immune complexes. d. the patient's prostaglandin (txa2) levels are abnormally high.

Question

Ryan Fischer

Biology

27 February, 19:38

Misinterpreting her physician's instructions, a 69-year-old woman with a history of peripheral artery disease has been taking two 325 mg tablets of aspirin daily. how has this most likely affected her hemostatic status? a. irreversible acetylation of platelet cyclooxygenase activity has occurred. b. she is at risk of developing secondary immune thrombocytopenic purpura (itp). c. the binding of an antibody to platelet factor iv produces immune complexes. d. the patient's prostaglandin (txa2) levels are abnormally high.

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Jeremy Keith · Answer 1

The answer is a.) irreversible acetylation of platelet cyclooxygenase activity has occurred. Studies who that aspirin intake (40 to 160 mg a day) can inhibit the cyclooxygenase activity of platelets by at least 80%. The effect lasts for the entire lifespan of a platelet which is approximately 8 to 9 days.