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17 December, 11:21

If you extract the DNA of the coliphage φ X174, you willfind that its composition is 25 percent A, 33 percent T, 24 percent G, and 18 percent C. Does this compositionmake sense in regard to Chargaff's rules? How wouldyou interpret this result? How might such a phage replicateits DNA?

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  1. 17 December, 11:37
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    This composition of nucleotide given in the question do not obey the chargaff"s rule.

    Explanation:

    According to chargaff"s rule the total number of purine bases will be same to the total number of pyrimidine bases that is

    Adenine+Guanine=Thymine+Cytosine

    But here the above quation is not maintained because according to the question A+G=49%

    and T+C = 51%.

    Such DNA is replicated by rolling circle model.
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